Research: Slow-release Nitric Oxide Particles May Reduce Inflammatory Acne

GW researcher and dermatologist, Adam Friedman, M.D., and colleagues, find that the release of nitric oxide over time may be a new way to treat and prevent acne through nanotechnology. This research, published in the Journal of Investigative Dermatology, identified that the nanoparticles were effective at killing Proprionobacterium acnes, the gram positive bacteria associated with acne, and even more importantly, they inhibited the damaging inflammation that result in the large, painful lesions associated with inflammatory acne.“Our understanding of acne has changed dramatically in the last 15-20 years,” said Friedman, associate professor of dermatology at the GW School of Medicine and Health Sciences and co-author of the study. “Inflammation is really the driving force behind all types of acne. In this paper, we provide an effective  a way to  kill the bacterium that serves as a stimulus for Acne without using an antibiotic, and demonstrate the means by which nitric oxide inhibits newly recognized pathways central to the formation of a pimple,  present in the skin even before you can see the acne.”Read more at Derm Wire.