Galderma Launches Alastin Restorative Eye Complex with TriHex+
Galderma announced the U.S. launch of Alastin Restorative Eye Complex with TriHex+. The new formula brings Alastin’s TriHex+ platform to a product developed to address visible signs of aging across the entire eye area, including the upper eyelid, under-eye and crow’s feet.
Visible signs of aging around the eyes can appear in several places at once: creasing on the upper eyelid, fine lines at the outer corners and puffiness beneath the eyes. Restorative Eye Complex with TriHex+ was developed to target the underlying biology of visible skin aging around the eyes, with clinically evaluated improvements in each area.
At the foundation of the enhanced formula is TriHex+, which combines Alastin’s TriHex Technology with proprietary Octapeptide-45. TriHex supports the body’s natural collagen and elastin production, while Octapeptide-45 helps the skin’s ability to naturally increase its own production of high-molecular-weight hyaluronic acid (HA) for visible plumping and hydration benefits.
Around the eyes, TriHex+ helps renew surface structure, supporting dermal-epidermal junction (DEJ) integrity and natural high-molecular-weight HA. It also helps refine contour by softening the visible transition from the lower eyelid to the cheek, including reduction in dark circles, hollowing and puffiness.
The formula also includes Acetyl Tetrapeptide-2, which supports lift. A proprietary dill and blackberry blend further supports natural elastin and protection to help maintain firmer-looking skin. Together with TriHex+, the blend works to maintain DEJ integrity, helping the formula visibly smooth, hydrate and strengthen the delicate eye area. These new technologies join the formula’s trusted foundation of mimosa tree extract, oak and green tea leaf extracts, niacinamide and the original TriHex Technology.
“Our work has always focused on amplifying the skin’s natural ability to regenerate itself, rather than simply covering up the signs of aging,” Alan D. Widgerow, MBBCH, MMED, FCS, FACS, Galderma’s chief scientific officer and head of the Skin Science Center for Innovation, shared in the release. “The skin around the eyes is thin and delicate, and it depends on collagen, elastin, and hyaluronic acid to stay firm and hydrated. With TriHex+™, we’re helping the skin with all three. And by addressing the upper eyelid, under-eye and crow’s feet individually, we can deliver meaningful, visible results in each of these key areas.”
The new formula was assessed in a large, robust clinical evaluation of 29 patients aged 35 to 70 with moderate-to-severe signs of aging around the eyes. The upper eyelid, lower eyelid and crow’s feet areas were evaluated separately using investigator clinical grading, clinical photography, subject self-assessment, and hydration and elasticity instrumentation.
At Week 12, investigator clinical grading showed a significant 30.13% improvement in crow’s feet fine lines and a 33.63% improvement in under-eye puffiness (p<0.0001 for both), and a substantial 21.62% decrease in upper-eyelid fine lines (p<0.0001).² Study participants experienced visibly reduced puffiness and a more refined lower-eye contour for a less tired look, along with a softened appearance of fine lines around the crow’s feet and smoother-looking wrinkles along the upper-eyelid crease.
Providers can also pair Restorative Eye Complex with TriHex+ with in-office treatments such as Restylane Eyelight, an FDA-approved hyaluronic acid filler for the improvement of infraorbital hollows.
Restorative Eye Complex with TriHex+ joins Regenerating Skin Nectar and Restorative Skin Complex in Alastin’s TriHex+ portfolio.
